CHEMBL389110


SMILES CC(=O)Nc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey DFLMNRNLACOXKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 462.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database