CHEMBL389718


SMILES CC(=O)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey NTIASQFANBLTMM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 447.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.38 8.38 8.38 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKd 7.6 7.6 7.6 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.17 7.17 7.17 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 5.61 5.61 5.61 ChEMBL