CHEMBL390213


SMILES O=C(CCCCCN1CCN(c2ccccn2)CC1)NC1CCCc2ccccc21
InChIKey XJYAXSYLDGSUII-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 406.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.44 7.44 7.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.44 7.44 7.44 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database