CHEMBL3908870


SMILES CC1(C)CC(=O)N(CCCCN2Cc3ccccc3C2)C(=O)C1
InChIKey HWHPJDOZGZLVJB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 314.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.13 7.16 8.2 ChEMBL
H1 HRH1 Human Histamine A pKi 5.41 5.41 5.41 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.52 6.53 6.53 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.53 5.53 5.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database