CHEMBL391703


SMILES O=C1NCN(c2ccccc2)C12CCN(C(c1ccc(F)cc1)c1ccc(F)cc1)CC2
InChIKey YROLXDODAUVJLI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 433.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.31 7.31 7.31 ChEMBL
δ OPRD Human Opioid A pKi 5.25 5.25 5.25 ChEMBL
μ OPRM Human Opioid A pKi 6.1 6.1 6.1 ChEMBL
κ OPRK Human Opioid A pKi 5.7 5.7 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database