CHEMBL3923145


SMILES O=C(CCOCCN1CCN(c2ccccc2-c2ccccc2)CC1)NCc1ccncc1
InChIKey MGBCSHBNZNTBPJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 444.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.61 5.61 5.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database