CHEMBL1221544


SMILES COc1ccccc1N1CCN(CCCNC(=O)c2ccc3ccccc3c2)CC1
InChIKey VSRXHPMNIVBYAT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.15 7.15 7.15 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.34 8.34 8.34 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database