CHEMBL1221593


SMILES COc1ccccc1N1CCN(CCCCCCNC(=O)c2ccc3ccccc3c2)CC1
InChIKey GNQMAWAOPDTCCX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 445.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.02 7.02 7.02 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.21 8.21 8.21 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.99 6.99 6.99 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database