CHEMBL4083727


SMILES Oc1ccc(N2CCN(CCCCOc3ccn4nccc4c3)CC2)c2c1OCCO2
InChIKey ASSMUHYHXZFLKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 4.72 4.72 4.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.8 6.8 6.8 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.28 5.28 5.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.96 7.06 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database