CHEMBL397550


SMILES COc1cc(Cl)c(CN(C(=O)CCCc2c[nH]c3ccccc23)C2CCC(CC3CCC(N)CC3)CC2)cc1OC
InChIKey CAGGFSBFLDCAIQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 579.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Mouse Melanocortin A pKi 5.68 5.7 5.72 ChEMBL
MC5 MC5R Human Melanocortin A pKi 5.05 5.21 5.37 ChEMBL
MC3 MC3R Human Melanocortin A pKi 4.6 4.61 4.62 ChEMBL
MC4 MC4R Human Melanocortin A pKi 5.64 5.73 5.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database