CHEMBL110489


SMILES C(#Cc1ccncc1)CCN1CC=C(c2ccccc2)CC1
InChIKey VPUYNZMAEQVXFX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 288.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.49 7.79 8.39 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.19 8.19 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 9.0 9.0 9.0 ChEMBL