CHEMBL3985152


SMILES COCOc1ccc(CNC(=O)CCCCCN2CCN(c3ccccc3-c3ccccc3)CC2)cc1
InChIKey HUFSUMIWNMPJOE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 13
Molecular weight (Da) 501.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.35 8.35 8.35 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.44 7.44 7.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database