CHEMBL3990525


SMILES O=C(CCCN1CCc2ccccc2CC1)c1ccc(Cl)cc1
InChIKey LQRMVBGKOMVMNF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 327.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.09 7.09 7.09 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.68 6.77 6.86 ChEMBL
H1 HRH1 Human Histamine A pKi 5.96 5.98 6.0 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.97 6.97 6.97 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.93 5.93 5.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database