CHEMBL3990801


SMILES Clc1cccc2c1CN(CCCCc1nc3ccccc3s1)CC2
InChIKey FKFXRRIOERUHEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 356.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.89 6.89 6.89 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.35 7.35 7.35 ChEMBL
H1 HRH1 Human Histamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.62 6.62 6.62 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.51 7.51 7.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.53 7.54 7.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database