CHEMBL3991133


SMILES O=C1c2ccc(Cl)cc2CC1CCN1CCc2ccccc2C1
InChIKey UEMSZTJJYVOVMY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 325.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.3 9.32 9.33 ChEMBL
H1 HRH1 Human Histamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.1 6.12 6.13 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.81 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.02 6.02 6.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database