CHEMBL3991166


SMILES COc1cc2c(cc1OC)CN(CCCCc1nc3cc(Cl)ccc3s1)CC2
InChIKey WVVWVIWPPSCORG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 416.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
H1 HRH1 Human Histamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.96 5.96 5.97 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.18 6.19 6.2 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database