CHEMBL3991400


SMILES Clc1ccc(C(=CCCN2CCc3ccccc3C2)c2ccc(Cl)cc2)cc1
InChIKey YFYVWKOXKJTAMY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 407.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
H1 HRH1 Human Histamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.69 5.69 5.69 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.8 6.81 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database