CHEMBL4176503
SMILES | Cc1noc(C)c1-c1ccc(C(=O)N2[C@H](C(=O)O)CS[C@@H]2c2ccccc2Cl)cc1 |
InChIKey | RZAMDGBOOPJHJQ-GHTZIAJQSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 1 |
Rotatable bonds | 4 |
Molecular weight (Da) | 442.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Structure pdb | 8J22 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FFA2 | FFAR2 | Human | Free fatty acid | A | pKi | 6.69 | 6.69 | 6.69 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FFA2 | FFAR2 | Mouse | Free fatty acid | A | pEC50 | 5.3 | 5.87 | 6.44 | ChEMBL |
FFA2 | FFAR2 | Human | Free fatty acid | A | pEC50 | 6.1 | 6.61 | 7.11 | ChEMBL |