CHEMBL420510


SMILES COc1ccccc1N1CCN(CCCCN2CCn3c(cc4ccccc43)C2=O)CC1
InChIKey BUVJSGDYMDZIDN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 432.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Rat Adrenoceptors A pKi 7.05 7.05 7.05 ChEMBL
D3 DRD3 Rat Dopamine A pKi 9.06 9.06 9.06 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.8 5.8 5.8 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.48 7.48 7.48 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.35 7.35 7.35 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.31 8.31 8.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database