CHEMBL423040


SMILES COc1cccc(C(=O)NCCCCN2CCN(c3noc4ccccc34)CC2)c1
InChIKey SXEFYDAWADNVLU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.33 7.33 7.33 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.12 8.12 8.12 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.11 5.11 5.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database