CHEMBL423735


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cnn3ccccc23)CC1
InChIKey MPDFDNDIHGRXBJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 407.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.85 7.85 7.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.96 7.08 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database