CHEMBL4249426


SMILES O=S(=O)(c1cccc2ncccc12)N1CCC[C@H]1CCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1
InChIKey STSNDGBQWCJPOF-QFIPXVFZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 520.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.11 7.11 7.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.84 6.84 6.84 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database