7α,25-dihydroxycholesterol
SMILES | O[C@H]1CC[C@]2(C(=C[C@H]([C@@H]3[C@@H]2CC[C@]2([C@H]3CC[C@@H]2[C@@H](CCCC(O)(C)C)C)C)O)C1)C |
InChIKey | BQMSKLCEWBSPPY-IKVTXIKFSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 3 |
Rotatable bonds | 5 |
Molecular weight (Da) | 418.3 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Endogenous |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GPR183 | GP183 | Human | A orphans | A | pIC50 | 7.15 | 8.38 | 9.62 | Guide to Pharmacology |
GPR183 | GP183 | Human | A orphans | A | pEC50 | 8.1 | 8.97 | 9.85 | Guide to Pharmacology |
GPR183 | GP183 | Human | A orphans | A | pEC50 | 9.85 | 10.17 | 10.49 | ChEMBL |
GPR183 | GP183 | Rat | A orphans | A | pEC50 | 8.88 | 8.88 | 8.88 | ChEMBL |
GPR183 | GP183 | Mouse | A orphans | A | pEC50 | 9.15 | 9.15 | 9.15 | ChEMBL |