CHEMBL412098


SMILES O=C1NCN(c2ccccc2)C12CCN([C@@H]1CC[C@H]3CCCc4cccc1c43)CC2
InChIKey JLFMYEAXZNPWBK-NFBKMPQASA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.41 9.41 9.41 ChEMBL
δ OPRD Human Opioid A pKi 5.86 5.86 5.86 ChEMBL
κ OPRK Human Opioid A pKi 7.05 7.05 7.05 ChEMBL
μ OPRM Human Opioid A pKi 7.33 7.33 7.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 8.36 8.36 8.36 ChEMBL
NOP OPRX Human Opioid A pEC50 7.41 7.41 7.41 ChEMBL