CHEMBL433741


SMILES COc1cccc(C(=O)NCCCCN2CCN(c3cccc(C)c3C)CC2)c1
InChIKey HDEPBPKSVYTTAM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 395.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 9.77 9.77 9.77 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.2 7.2 7.2 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.11 7.11 7.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database