CHEMBL413343


SMILES CNc1cc(OC)c(C(=O)NC[C@H]2CN(Cc3ccccc3)C[C@@H]2C)cc1Cl
InChIKey RVBDWZKWSXQLMF-RDJZCZTQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.7 4.7 4.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.5 6.5 6.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.48 6.7 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database