CHEMBL4164541


SMILES CCc1nc2c(N3CCNCC3)ccnc2n1Cc1cccc(Cl)c1
InChIKey UDRACXACDCFKNK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.06 5.06 5.06 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.87 5.87 5.87 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.21 5.21 5.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.29 7.29 7.29 ChEMBL