CHEMBL418020


SMILES O=C1NCN(c2ccccc2)C12CCN([C@@H]1CCc3c(Cl)ccc(Cl)c3C1)CC2
InChIKey GKBLBGBXCLKVGY-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 429.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.68 7.68 7.68 ChEMBL
δ OPRD Human Opioid A pKi 6.23 6.23 6.23 ChEMBL
κ OPRK Human Opioid A pKi 7.33 7.33 7.33 ChEMBL
μ OPRM Human Opioid A pKi 8.08 8.08 8.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database