CHEMBL420863


SMILES Cc1ccc2nc(O)n(C3CCN(Cc4cc5c(cc4Cl)OCO5)CC3)c2c1
InChIKey PAJSQNJPMJTKTN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 399.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 6.55 6.55 6.55 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.18 6.18 6.18 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 6.25 6.25 6.25 ChEMBL
δ OPRD Human Opioid A pIC50 6.93 6.93 6.93 ChEMBL
κ OPRK Human Opioid A pIC50 8.54 8.54 8.54 ChEMBL
μ OPRM Human Opioid A pIC50 8.62 8.62 8.62 ChEMBL