CHEMBL4210782


SMILES Cc1ccc(-c2n[nH]c3c2CCNCC3)cc1
InChIKey LWNZEHWQIHUHGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 227.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 6.78 6.78 6.78 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.59 5.59 5.59 ChEMBL