CHEMBL4216126


SMILES CC(C)c1ccccc1OCCCN1CCC(NS(=O)(=O)c2ccc(F)cc2)CC1
InChIKey VSRQIONFRPRLGS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 434.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.68 5.68 5.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database