CHEMBL423361


SMILES O=C(C1CCCCC1)N(CCN1CCN(c2ccccc2O)CC1)c1ccccn1
InChIKey GSYXUBWRYIWXJK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 408.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.44 6.44 6.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.85 9.27 9.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 8.68 8.68 8.68 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 9.11 9.11 9.11 ChEMBL