CHEMBL4240910


SMILES O=c1[nH]c2c(N3CCN(CC[C@@H]4CCCN4S(=O)(=O)c4cccc5ncccc45)CC3)cccc2o1
InChIKey XDVPBSXXZFHLIM-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 507.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.41 5.41 5.41 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.61 5.61 5.61 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.05 8.05 8.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database