CHEMBL4242392


SMILES O=S(=O)(c1cccc2cnccc12)N1CCC[C@H]1CCN1CCN(c2nsc3ccccc23)CC1
InChIKey TVTKXMSEQXXPJA-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 507.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database