CHEMBL426900


SMILES Cc1ccc(-c2ccccc2OC(C)C2=NCCN2)cc1
InChIKey FVORBSYXXHDBGZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 280.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.4 6.4 6.4 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.6 6.6 6.6 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 6.08 6.08 6.08 ChEMBL