CHEMBL427555


SMILES COc1cccc(CN2CC[C@H](NC(=O)c3ccc(-c4cccs4)cc3)C2)c1
InChIKey CIYMLKKXWWZEQT-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.35 5.35 5.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database