CHEMBL428563


SMILES O=C1NCN(c2ccccc2)C12CCN(C(c1ccccc1)c1ccccc1Cl)CC2
InChIKey WQORCLHRRWRFRW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 431.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.05 8.05 8.05 ChEMBL
δ OPRD Human Opioid A pKi 4.83 4.83 4.83 ChEMBL
κ OPRK Human Opioid A pKi 5.96 5.96 5.96 ChEMBL
μ OPRM Human Opioid A pKi 6.11 6.11 6.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database