CHEMBL4287471


SMILES COc1cc2c(cc1O)CN(CCCCNC(=O)c1ccc(-c3ccccc3)cc1)CC2
InChIKey WLGXAVSOEWKYQS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 430.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.14 6.14 6.14 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.57 8.57 8.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database