CHEMBL429136


SMILES CC1NC(NCC(F)F)=Nc2ccc(Cl)c(Cl)c21
InChIKey KNZNKJDEMHGXSO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 293.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.63 7.63 7.63 ChEMBL
H1 HRH1 Human Histamine A pKi 7.74 7.74 7.74 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database