CHEMBL1257689


SMILES Cc1ccc(C)c(C2(O)CCN(CCCC(=O)c3ccc(F)cc3)CC2)c1
InChIKey ZRBHAKYJDKFUAO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 7.72 7.72 7.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.57 7.57 7.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.19 8.33 8.47 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database