CHEMBL4596341


SMILES CCCN(CCCCNC(=O)c1cc2ccccc2[nH]1)C[C@H]1C[C@@H]1c1cccc(Cl)c1Cl
InChIKey OXKMARLXXNQVMY-CTNGQTDRSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.17 6.17 6.17 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.21 7.21 7.21 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.89 7.89 7.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 5.59 5.59 5.59 ChEMBL
D3 DRD3 Human Dopamine A pEC50 6.0 6.42 6.84 ChEMBL