CHEMBL4437912


SMILES CCc1cccc(NC(=O)CN2CCC(c3ccccn3)CC2)c1
InChIKey OKFIQGYGZIGIDI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 323.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.08 7.08 7.08 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.3 6.3 6.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.94 5.94 5.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 6.27 6.27 6.27 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.58 5.65 5.72 ChEMBL
D2 DRD2 Human Dopamine A pIC50 4.17 4.48 4.79 ChEMBL