CHEMBL4440130


SMILES COc1ccc2c(c1)c(C1=CCNCC1)cn2S(=O)(=O)c1cccc2ncccc12
InChIKey RQZXKTXKVVCWAG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 419.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.81 5.81 5.81 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.53 5.53 5.53 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.52 6.52 6.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database