CHEMBL465054


SMILES CN1CCc2cc(-c3ccccc3)cc3c2[C@H]1Cc1ccc(O)c(O)c1-3
InChIKey NJWHLJABYCIZPL-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.11 8.11 8.11 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.93 7.93 7.93 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.06 7.06 7.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pIC50 7.83 7.83 7.83 ChEMBL
D2 DRD2 Rat Dopamine A pEC50 7.64 7.64 7.64 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.63 7.63 7.63 ChEMBL