CHEMBL4470304


SMILES O=C1c2cccc3cccc(c23)N1CCCCCCN1CCN(c2ncccn2)CC1
InChIKey VJGYBRVHAUSTAR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.28 5.28 5.28 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.73 6.73 6.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database