CHEMBL471262


SMILES CCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey JNSDWRYEOZHWLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 431.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.27 8.27 8.27 ChEMBL
δ OPRD Human Opioid A pKi 5.51 5.51 5.51 ChEMBL
κ OPRK Human Opioid A pKi 5.86 5.86 5.86 ChEMBL
μ OPRM Human Opioid A pKi 6.85 6.85 6.85 ChEMBL
NOP OPRX Human Opioid A pKi 8.27 8.27 8.27 PDSP Ki database
κ OPRK Human Opioid A pKi 5.86 5.86 5.86 PDSP Ki database
δ OPRD Human Opioid A pKi 5.51 5.51 5.51 PDSP Ki database
μ OPRM Human Opioid A pKi 6.85 6.85 6.85 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database