CHEMBL4746800


SMILES CN(C)CCN1C(=O)c2ccccc2/C=C\c2ccccc21
InChIKey YFINOLWYBYMFPQ-QXMHVHEDSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 292.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.07 4.07 4.07 ChEMBL
H1 HRH1 Human Histamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.7 4.7 4.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.13 4.13 4.13 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.11 4.11 4.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.94 4.94 4.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database