CHEMBL4748379


SMILES Cc1ccc2sc(S(=O)(=O)N[C@@H]3CCN(CCCc4noc5ccccc45)C3)cc2c1
InChIKey JWFVGFMQWYTGRI-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 455.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.64 6.64 6.64 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.23 9.23 9.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.76 8.76 8.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database