CHEMBL477206


SMILES COc1ccccc1N1CCN(CCCCN2CCCc3ccccc3C2=O)CC1
InChIKey USGFBEWNXKQBDG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 407.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.96 5.96 5.96 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.54 5.54 5.54 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.57 5.57 5.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.8 9.19 9.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.41 8.56 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 9.48 9.48 9.48 ChEMBL