CHEMBL4574793


SMILES O=C(CCCN1CCCN(c2ccc(Cl)cn2)CC1)c1ccc(F)cc1
InChIKey KVGNSDMVYWRLTG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.58 7.58 7.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.39 7.39 7.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database